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Sep 28

Discovery Foundation Models: Toward Open-Ended Discovery Intelligence

Foundation models have progressed from learning and reasoning over existing knowledge, to increasingly learning through action, tool use, and outcome feedback. We argue that the next frontier is a further transition: from solving and acting within problems specified by humans to participating in the process by which new problems, representations, explanations, and knowledge are created. We refer to this capability as Discovery Intelligence. We formulate Discovery Foundation Models (DFMs) as general-purpose model systems for open-ended discovery. A DFM operates over a revisable research state and supports seven coupled capabilities spanning problem discovery, formulation, representation construction, hypothesis formation, intervention, evidence-grounded revision, and continual discovery improvement. We instantiate this framework with Zetema, which couples explicit research-state dynamics, verification and experimental gating, external grounding, and cross-task Discovery Skill evolution. We further ground the framework with GALILEO, a real therapeutic-discovery system in which Dry-Lab reasoning, robotic and hands-on Wet-Lab experimentation, external biological evidence, and iterative hypothesis and design revision form a closed physical discovery loop. We then formulate a unified approach to capability formation and process-centered evaluation, enabling discovery behavior to be trained, improved, and measured beyond final-answer performance. Together, these components establish discovery as a learnable, executable, and evaluable capability of foundation-model systems. We view this shift as a broader progression in intelligence scaling: from learning over existing knowledge, to learning from action outcomes, and ultimately to participating in the construction, testing, and revision of the structures through which new knowledge is discovered. Code: https://github.com/Gen-Verse/DFM-Plans

  • 3 authors
·
Sep 13 3

Pioneer Agent: Continual Improvement of Small Language Models in Production

Small language models are attractive for production deployment due to their low cost, fast inference, and ease of specialization. However, adapting them to a specific task remains a challenging engineering loop, driven not by training itself but by surrounding decisions: data curation, failure diagnosis, regression avoidance, and iteration control. We present Pioneer Agent, a closed-loop system that automates this lifecycle. In cold-start mode, given only a natural-language task description, the agent acquires data, constructs evaluation sets, and iteratively trains models by jointly optimizing data, hyperparameters, and learning strategy. In production mode, given a deployed model with labeled failures, it diagnoses error patterns, constructs targeted training data, and retrains under explicit regression constraints. To evaluate this setting, we introduce AdaptFT-Bench, a benchmark of synthetic inference logs with progressively increasing noise, designed to test the full adaptation loop: diagnosis, curriculum synthesis, retraining, and verification. Across eight cold-start benchmarks spanning reasoning, math, code generation, summarization, and classification, Pioneer Agent improves over base models by 1.6-83.8 points. On AdaptFT-Bench, it improves or preserves performance in all seven scenarios, while naive retraining degrades by up to 43 points. On two production-style deployments built from public benchmark tasks, it raises intent classification from 84.9% to 99.3% and Entity F1 from 0.345 to 0.810. Beyond performance gains, the agent often discovers effective training strategies, including chain-of-thought supervision, task-specific optimization, and quality-focused data curation, purely from downstream feedback.

  • 8 authors
·
Apr 9

Rethinking Continual Experience Internalization for Self-Evolving LLM Agents

Experience internalization converts contextual experience from past interactions into reusable parametric capability, offering a promising path toward continual learning in large language models (LLMs). While prior work has predominantly focused on single-iteration transfer, we discover that under multi-iteration experience learning, existing methods suffer from a progressive capability collapse rather than compounding improvement. We systematically examine this failure through three vital dimensions of experience internalization: (1) Experience Granularity: We find that principle-level experience is more durable than instance-level experience, as it effectively abstracts transferable strategies away from trajectory-specific details. (2) Experience Injection Pattern: Our analysis reveals that step-wise injection significantly outperforms global injection by aligning experience with intermediate decision states, a property that is critical for long-horizon tool use. (3) Internalization Regime: We demonstrate that off-policy context-distillation on high-quality teacher trajectories provides a substantially more stable training signal than on-policy context-distillation, which is inherently limited by local corrections on student-induced flawed states. Together, these insights yield a simple yet robust recipe for stable and sustainable experience internalization, providing concrete guidance for engineering self-evolving and continually learning LLMs.

  • 10 authors
·
Jun 2 2

Learning to Discover at Test Time

How can we use AI to discover a new state of the art for a scientific problem? Prior work in test-time scaling, such as AlphaEvolve, performs search by prompting a frozen LLM. We perform reinforcement learning at test time, so the LLM can continue to train, but now with experience specific to the test problem. This form of continual learning is quite special, because its goal is to produce one great solution rather than many good ones on average, and to solve this very problem rather than generalize to other problems. Therefore, our learning objective and search subroutine are designed to prioritize the most promising solutions. We call this method Test-Time Training to Discover (TTT-Discover). Following prior work, we focus on problems with continuous rewards. We report results for every problem we attempted, across mathematics, GPU kernel engineering, algorithm design, and biology. TTT-Discover sets the new state of the art in almost all of them: (i) Erdős' minimum overlap problem and an autocorrelation inequality; (ii) a GPUMode kernel competition (up to 2times faster than prior art); (iii) past AtCoder algorithm competitions; and (iv) denoising problem in single-cell analysis. Our solutions are reviewed by experts or the organizers. All our results are achieved with an open model, OpenAI gpt-oss-120b, and can be reproduced with our publicly available code, in contrast to previous best results that required closed frontier models. Our test-time training runs are performed using Tinker, an API by Thinking Machines, with a cost of only a few hundred dollars per problem.

A Comprehensive Survey of Continual Learning: Theory, Method and Application

To cope with real-world dynamics, an intelligent system needs to incrementally acquire, update, accumulate, and exploit knowledge throughout its lifetime. This ability, known as continual learning, provides a foundation for AI systems to develop themselves adaptively. In a general sense, continual learning is explicitly limited by catastrophic forgetting, where learning a new task usually results in a dramatic performance degradation of the old tasks. Beyond this, increasingly numerous advances have emerged in recent years that largely extend the understanding and application of continual learning. The growing and widespread interest in this direction demonstrates its realistic significance as well as complexity. In this work, we present a comprehensive survey of continual learning, seeking to bridge the basic settings, theoretical foundations, representative methods, and practical applications. Based on existing theoretical and empirical results, we summarize the general objectives of continual learning as ensuring a proper stability-plasticity trade-off and an adequate intra/inter-task generalizability in the context of resource efficiency. Then we provide a state-of-the-art and elaborated taxonomy, extensively analyzing how representative methods address continual learning, and how they are adapted to particular challenges in realistic applications. Through an in-depth discussion of promising directions, we believe that such a holistic perspective can greatly facilitate subsequent exploration in this field and beyond.

  • 4 authors
·
Jan 31, 2023

Evidence-Informed LLM Beliefs for Continual Scientific Discovery

Open-ended scientific discovery with large language models (LLMs) increasingly operates as a long-horizon loop of hypothesis search and verification, where a reward signal guides which hypotheses to test next. A notable recent example is AutoDiscovery, which uses "Bayesian surprise" - the belief shift an LLM undergoes after observing evidence for a hypothesis - as both a discovery metric and a reward for search. We first observe that AutoDiscovery treats surprisal as a static quantity, while surprisal in human reasoning is non-stationary - it is defined relative to beliefs that evolve with experience, a prerequisite for continual scientific discovery. We address this mismatch with evidence-informed LLM beliefs: priors updated with evidence from previous hypotheses to compute non-stationary surprisal for new hypotheses. We compare in-context belief-updating mechanisms and find that embedding-based retrieval-augmented generation over prior discoveries best anticipates eventual posteriors, identifying 37.5% of static surprisals as spurious. We then modify search to avoid these spurious rewards and prioritize hypotheses that remain surprising under non-stationary beliefs. Concretely, we introduce two complementary changes to the original search procedure: belief-update filtering and diversity maximization. Across five discovery domains, our method increases accumulated non-stationary surprisal by 30.62% on average compared to the original search procedure, demonstrating that continual scientific discovery with LLMs requires not only better belief measurement but also search procedures that avoid redundancy and encourage diversity.

  • 6 authors
·
Jun 27

Root-Cause Attribution Is a Search Problem: Continual Search for Long-Horizon Agent Failures

The increasing deployment of AI agents in long-horizon tasks yields massive execution logs. Diagnosing failures within these records is crucial for reliability, as it transforms outcome-level signals into actionable interventions. The sheer scale of the data renders human review impractical, driving the need for automated root-cause attribution (RCA). However, automated RCA methods using LLMs suffer from low diagnostic accuracy, especially as execution traces grow larger. They struggle because relevant information is often sparse, distributed across distant actions, and disconnected from the visible failure, reducing root-cause attribution to a massive search problem. Existing RCA methods typically rely on one-shot LLM judgments to diagnose failures from execution traces. While effective for shorter trajectories, these judges tend to settle on a plausible diagnosis early, leaving critical evidence in longer traces unexamined. We introduce Continual Search, an iterative framework that nudges the judge, over successive turns, to keep searching for unresolved diagnostic evidence. We evaluate Continual Search across four existing RCA benchmarks. Recognizing the lack of massive execution traces in current benchmarks, we introduce MegaRCA-Mix to evaluate RCA at scale. MegaRCA-Mix provides a challenging testbed of 50 human-annotated failure trials spanning long-horizon, execution-heavy tasks. Across multiple benchmark suites and model families, Continual Search consistently improves attribution performance. On MegaRCA-Mix, for example, it improves GPT-5.5's F1 score by more than 40\%, from 0.349 to 0.498. More interestingly, within the same model family, lower-tier models can even surpass their higher-tier counterparts, demonstrating that effective search supersedes raw model scale.

ScaleAI Scale AI
·
Sep 10 2

SciPaths: Forecasting Pathways to Scientific Discovery

Scientific progress depends on sequences of enabling contributions, yet existing AI4Science benchmarks largely focus on citation prediction, literature retrieval, or idea generation rather than the dependencies that make progress possible. In this paper, we introduce discovery pathway forecasting: given a target scientific contribution and the prior literature available at a specified time, the task is to (1) identify the enabling contributions required to realize it and (2) ground each in prior work when such prior work exists. We present SciPaths, a benchmark of 262 expert-annotated gold pathways and 2,444 silver pathways constructed from machine learning and natural language processing papers, where each pathway records enabling contributions, roles, rationales, and prior-work groundings or unmapped decisions. Evaluating frontier and open-weight language models, we find that the best model reaches only 0.189 F1 under strict semantic matching, with core methodological dependencies hardest to recover. Prior-work grounding improves substantially when gold enabling contributions are provided, showing that decomposition quality is a major bottleneck for end-to-end pathway recovery. SciPaths therefore shifts evaluation toward a missing capability in scientific forecasting: reasoning backward from a target contribution to the enabling scientific building blocks and prior-work dependencies that make it feasible.

  • 7 authors
·
May 13

Continual Learning Bench: Evaluating Frontier AI Systems in Real-World Stateful Environments

Continual learning, the ability of AI systems to improve through sequential experience, has attracted substantial interest, but no high-quality benchmark exists to evaluate it. We introduce Continual Learning Bench (CL-Bench), the first difficult, expert-validated benchmark designed to measure whether LLM-based systems genuinely improve with experience. CL-Bench spans six diverse domains (software engineering, signal processing, disease outbreak forecasting, database querying, strategic game-playing, and demand forecasting), each validated by domain experts and designed so that tasks share a learnable latent structure (codebase layout, disease outbreak dynamics, opponent strategies) that a stateful system can discover online but a stateless one cannot. We evaluate frontier models across several agent architectures, from naive in-context learning (ICL) to dedicated memory systems, introducing a gain metric to isolate learning from prior capabilities. We find that these systems leave headroom for improved continual learning: agents frequently overfit to immediate observations or fail to reuse knowledge across instances, and dedicated memory systems do not fix this -- in fact, naive ICL outperforms systems dedicated to memory management. CL-Bench is the first benchmark to evaluate continual learning across diverse real-world domains with expert-validated tasks and isolate online learning from underlying model capability, showing a need for better continual learning systems.

  • 10 authors
·
Jun 3

Evaluation-driven Scaling for Scientific Discovery

Language models are increasingly used in scientific discovery to generate hypotheses, propose candidate solutions, implement systems, and iteratively refine them. At the core of these trial-and-error loops lies evaluation: the process of obtaining feedback on candidate solutions via verifiers, simulators, or task-specific scoring functions. While prior work has highlighted the importance of evaluation, it has not explicitly formulated the problem of how evaluation-driven discovery loops can be scaled up in a principled and effective manner to push the boundaries of scientific discovery, a problem this paper seeks to address. We introduce Simple Test-time Evaluation-driven Scaling (SimpleTES), a general framework that strategically combines parallel exploration, feedback-driven refinement, and local selection, revealing substantial gains unlocked by scaling evaluation-driven discovery loops along the right dimensions. Across 21 scientific problems spanning six domains, SimpleTES discovers state-of-the-art solutions using gpt-oss models, consistently outperforming both frontier-model baselines and sophisticated optimization pipelines. Particularly, we sped up the widely used LASSO algorithm by over 2x, designed quantum circuit routing policies that reduce gate overhead by 24.5%, and discovered new Erdos minimum overlap constructions that surpass the best-known results. Beyond novel discoveries, SimpleTES produces trajectory-level histories that naturally supervise feedback-driven learning. When post-trained on successful trajectories, models not only improve efficiency on seen problems but also generalize to unseen problems, discovering solutions that base models fail to uncover. Together, our results establish effective evaluation-driven loop scaling as a central axis for advancing LLM-driven scientific discovery, and provide a simple yet practical framework for realizing these gains.

  • 25 authors
·
Apr 20 2

Self-Evolving Recommendation System: End-To-End Autonomous Model Optimization With LLM Agents

Optimizing large-scale machine learning systems, such as recommendation models for global video platforms, requires navigating a massive hyperparameter search space and, more critically, designing sophisticated optimizers, architectures, and reward functions to capture nuanced user behaviors. Achieving substantial improvements in these areas is a non-trivial task, traditionally relying on extensive manual iterations to test new hypotheses. We propose a self-evolving system that leverages Large Language Models (LLMs), specifically those from Google's Gemini family, to autonomously generate, train, and deploy high-performing, complex model changes within an end-to-end automated workflow. The self-evolving system is comprised of an Offline Agent (Inner Loop) that performs high-throughput hypothesis generation using proxy metrics, and an Online Agent (Outer Loop) that validates candidates against delayed north star business metrics in live production. Our agents act as specialized Machine Learning Engineers (MLEs): they exhibit deep reasoning capabilities, discovering novel improvements in optimization algorithms and model architecture, and formulating innovative reward functions that target long-term user engagement. The effectiveness of this approach is demonstrated through several successful production launches at YouTube, confirming that autonomous, LLM-driven evolution can surpass traditional engineering workflows in both development velocity and model performance.

  • 5 authors
·
Feb 10

AgentRxiv: Towards Collaborative Autonomous Research

Progress in scientific discovery is rarely the result of a single "Eureka" moment, but is rather the product of hundreds of scientists incrementally working together toward a common goal. While existing agent workflows are capable of producing research autonomously, they do so in isolation, without the ability to continuously improve upon prior research results. To address these challenges, we introduce AgentRxiv-a framework that lets LLM agent laboratories upload and retrieve reports from a shared preprint server in order to collaborate, share insights, and iteratively build on each other's research. We task agent laboratories to develop new reasoning and prompting techniques and find that agents with access to their prior research achieve higher performance improvements compared to agents operating in isolation (11.4% relative improvement over baseline on MATH-500). We find that the best performing strategy generalizes to benchmarks in other domains (improving on average by 3.3%). Multiple agent laboratories sharing research through AgentRxiv are able to work together towards a common goal, progressing more rapidly than isolated laboratories, achieving higher overall accuracy (13.7% relative improvement over baseline on MATH-500). These findings suggest that autonomous agents may play a role in designing future AI systems alongside humans. We hope that AgentRxiv allows agents to collaborate toward research goals and enables researchers to accelerate discovery.

  • 2 authors
·
Mar 23, 2025 2

Recursive self-improvement of AI research agents

AI agents are beginning to automate research and development across the AI stack, from improving training efficiency to optimizing inference. A natural next step is to improve the research efficiency of the agents themselves. When an AI research agent's own code is the object of optimization, each accepted rewrite becomes the agent that the next round edits. We refer to this loop as recursive self-improvement. Its significance lies in a long-standing trend, in which increased cumulative spending on R&D yields diminishing returns. Sustained self-improvement offers a way to counter this trend. We present AIDE^2, a system that implements this loop for a frontier AI research agent. It proposes changes to its own code, benchmarks modified versions of itself on a suite of AI R&D tasks, and keeps the changes that perform best on hidden evaluations. In an autonomous 8-day run, AIDE^2 discovered seven successive improvements, ranging from a new search policy to memory mechanisms that compress and manage the agent's growing context. These gains generalize to four held-out benchmarks spanning machine learning engineering, heuristic algorithm engineering, and physics-based weather forecasting, the last of which is out of distribution from the selection tasks. On all four, the strongest discovered agent matches or exceeds a human-engineered production research agent that ranks among the strongest on FML-Bench. On a separate held-out task family, the discovered agents also exhibit reduced reward hacking, a property the loop never explicitly optimized for: the rate falls from 55% to 32% during the run, 7 percentage points below the human-engineered agent. Together, these results show that an AI research agent can improve its own research efficiency through recursive self-improvement, and that these gains transfer to tasks and domains the loop never encountered.

WecoAI Weco AI
·
Sep 21 1

Continual Learning of Large Language Models: A Comprehensive Survey

The recent success of large language models (LLMs) trained on static, pre-collected, general datasets has sparked numerous research directions and applications. One such direction addresses the non-trivial challenge of integrating pre-trained LLMs into dynamic data distributions, task structures, and user preferences. Pre-trained LLMs, when tailored for specific needs, often experience significant performance degradation in previous knowledge domains -- a phenomenon known as "catastrophic forgetting". While extensively studied in the continual learning (CL) community, it presents new manifestations in the realm of LLMs. In this survey, we provide a comprehensive overview of the current research progress on LLMs within the context of CL. This survey is structured into four main sections: we first describe an overview of continually learning LLMs, consisting of two directions of continuity: vertical continuity (or vertical continual learning), i.e., continual adaptation from general to specific capabilities, and horizontal continuity (or horizontal continual learning), i.e., continual adaptation across time and domains (Section 3). We then summarize three stages of learning LLMs in the context of modern CL: Continual Pre-Training (CPT), Domain-Adaptive Pre-training (DAP), and Continual Fine-Tuning (CFT) (Section 4). Then we provide an overview of evaluation protocols for continual learning with LLMs, along with the current available data sources (Section 5). Finally, we discuss intriguing questions pertaining to continual learning for LLMs (Section 6). The full list of papers examined in this survey is available at https://github.com/Wang-ML-Lab/llm-continual-learning-survey.

  • 9 authors
·
Apr 25, 2024

Happy: A Debiased Learning Framework for Continual Generalized Category Discovery

Constantly discovering novel concepts is crucial in evolving environments. This paper explores the underexplored task of Continual Generalized Category Discovery (C-GCD), which aims to incrementally discover new classes from unlabeled data while maintaining the ability to recognize previously learned classes. Although several settings are proposed to study the C-GCD task, they have limitations that do not reflect real-world scenarios. We thus study a more practical C-GCD setting, which includes more new classes to be discovered over a longer period, without storing samples of past classes. In C-GCD, the model is initially trained on labeled data of known classes, followed by multiple incremental stages where the model is fed with unlabeled data containing both old and new classes. The core challenge involves two conflicting objectives: discover new classes and prevent forgetting old ones. We delve into the conflicts and identify that models are susceptible to prediction bias and hardness bias. To address these issues, we introduce a debiased learning framework, namely Happy, characterized by Hardness-aware prototype sampling and soft entropy regularization. For the prediction bias, we first introduce clustering-guided initialization to provide robust features. In addition, we propose soft entropy regularization to assign appropriate probabilities to new classes, which can significantly enhance the clustering performance of new classes. For the harness bias, we present the hardness-aware prototype sampling, which can effectively reduce the forgetting issue for previously seen classes, especially for difficult classes. Experimental results demonstrate our method proficiently manages the conflicts of C-GCD and achieves remarkable performance across various datasets, e.g., 7.5% overall gains on ImageNet-100. Our code is publicly available at https://github.com/mashijie1028/Happy-CGCD.

  • 6 authors
·
Oct 9, 2024

Toward Generalist Autonomous Research via Hypothesis-Tree Refinement

Scientific progress depends on a repeated loop of exploration, experimentation, and abstraction. Researchers test candidate directions, interpret the evidence, and carry the resulting lessons into later attempts. We study how an AI agent can run this loop autonomously over long horizons. We introduce Arbor, a general framework for autonomous research that combines a long-lived coordinator, short-lived executors, and Hypothesis Tree Refinement (HTR), a persistent tree that links hypotheses, artifacts, evidence, and distilled insights across time. The coordinator manages global research strategy over the tree, while executors implement and test individual hypotheses in isolated worktrees. As results return, Arbor updates the tree, propagates reusable lessons, refines the search frontier, and admits verified improvements. This design turns autonomous research from a sequence of local attempts into a cumulative process in which strategy, execution, and evidence are carried across time. We evaluate Arbor under Autonomous Optimization (AO), an operational setting where an agent improves an initial research artifact through iterative experimentation without step-level human supervision. Across six real research tasks in model training, harness engineering, and data synthesis, Arbor achieves the best held-out result on all six tasks, attaining more than 2.5x the average relative held-out gain of Codex and Claude Code under the same task interface and resource budget. On MLE-Bench Lite, Arbor reaches 86.36% Any Medal with GPT-5.5, the strongest result in our comparison.

Ask Only When Needed: Proactive Retrieval from Memory and Skills for Experience-Driven Lifelong Agents

Online lifelong learning enables agents to accumulate experience across interactions and continually improve on long-horizon tasks. However, existing methods typically treat retrieval from past experience as a passive operation, triggering it only at task initialization or after completing a step. Consequently, agents often fail to identify knowledge gaps during interaction and proactively retrieve the most useful experience for the current decision. To address this limitation, we present ProactAgent, an experience-driven lifelong learning framework for proactive retrieval over a structured experience base. We first introduce Experience-Enhanced Online Evolution (ExpOnEvo), which enables continual improvement through both policy updates and memory refinement. The experience base organizes historical interactions into typed repositories, including factual memory, episodic memory, and behavioral skills, so that retrieval can provide both relevant evidence and actionable guidance. On top of this, we propose Proactive Reinforcement Learning-based Retrieval (ProactRL), which models retrieval as an explicit policy action and learns when and what to retrieve via paired-branch process rewards. By comparing continuations from identical interaction prefixes with and without retrieval, ProactRL provides step-level supervision for retrieval decisions, encouraging retrieval only when it leads to better task outcomes or higher efficiency. Experiments on SciWorld, AlfWorld, and StuLife show that ProactAgent consistently improves lifelong agent performance, achieving success rates of 73.50\% on SciWorld and 71.28\% on AlfWorld while substantially reducing retrieval overhead, and attains performance competitive with proprietary models on StuLife.

  • 4 authors
·
Apr 21

FlyPrompt: Brain-Inspired Random-Expanded Routing with Temporal-Ensemble Experts for General Continual Learning

General continual learning (GCL) challenges intelligent systems to learn from single-pass, non-stationary data streams without clear task boundaries. While recent advances in continual parameter-efficient tuning (PET) of pretrained models show promise, they typically rely on multiple training epochs and explicit task cues, limiting their effectiveness in GCL scenarios. Moreover, existing methods often lack targeted design and fail to address two fundamental challenges in continual PET: how to allocate expert parameters to evolving data distributions, and how to improve their representational capacity under limited supervision. Inspired by the fruit fly's hierarchical memory system characterized by sparse expansion and modular ensembles, we propose FlyPrompt, a brain-inspired framework that decomposes GCL into two subproblems: expert routing and expert competence improvement. FlyPrompt introduces a randomly expanded analytic router for instance-level expert activation and a temporal ensemble of output heads to dynamically adapt decision boundaries over time. Extensive theoretical and empirical evaluations demonstrate FlyPrompt's superior performance, achieving up to 11.23%, 12.43%, and 7.62% gains over state-of-the-art baselines on CIFAR-100, ImageNet-R, and CUB-200, respectively. Our source code is available at https://github.com/AnAppleCore/FlyGCL.

  • 6 authors
·
Feb 2

Folding, Reasoning, and Scaling with Open-source Drug Discovery Engine

Accurately modeling biomolecular interactions is a central bottleneck in biology and therapeutic discovery. Here, we introduce Open Drug Discovery Engine (OpenDDE), an open-source, all-atom biomolecular foundation model that uses co-folding as the entry point to a scalable AI-driven drug discovery engine. Rather than treating structure prediction as an isolated endpoint, OpenDDE is designed as a shared structural reasoning layer for modeling sequence-structure-function relationships across biomolecular complexes, enabling complex structure prediction today while providing a foundation for de novo design, affinity estimation, structure-conditioned optimization, and more. OpenDDE integrates advances in all-atom architecture, atomic latent reasoning, inference optimization, and large-scale data processing to achieve IsoDDE-level co-folding accuracy within a reproducible and openly accessible framework. We also identify two scaling-law directions for co-folding models, revealing practical routes for continued improvement through data, model, inference, and training scaling. By releasing training code, inference pipelines, checkpoints, and benchmarks, OpenDDE aims to democratize access to frontier biomolecular intelligence, accelerate global collaboration, and lay an open foundation for next-generation drug discovery systems that can move from predicting molecular structures toward designing, scoring, and optimizing therapeutic candidates for human health.

  • 1 authors
·
Jul 3

ExplorationBench: Measuring AI Systems' Exploration in Verifiable Alien Worlds

Scientific discovery begins where known problems end. There, AI systems must engage in exploration: framing hypotheses, designing experiments, and iterating on the results. However, evaluating this ability is difficult: (1) how to verify whether a genuinely new hypothesis holds, and (2) how to determine whether a system has discovered it through exploration or merely recalled related knowledge from pre-training data. To this end, we introduce ExplorationBench, which turns the wicked problem of evaluating scientific exploration into a concrete and tractable framework built on verifiable Alien Worlds: their rules are executable, so every answer can be checked exactly, and they conflict with familiar knowledge, so recall alone cannot solve the tasks. The benchmark contains two sandboxes, AlienCode (31 discovery targets, 70 tasks) and AlienLogic (24 discovery targets, 70 tasks). Each sandbox provides a flawed manual, task-specific environmental feedback, and a dedicated tool-call schema. Systems use these resources to explore the sandbox, then solve held-out tasks. We evaluate 10 AI systems and find that the strongest systems can acquire and apply unfamiliar rules, while performance varies substantially across trajectories and continued exploration can stall or reverse earlier gains. ExplorationBench represents a step towards AI systems that can acquire and apply genuinely new knowledge through exploration in unknown environments.

Dream-RSI: Recursive Self-Improvement through Evolving Worlds

Recursive self-improvement is becoming increasingly vital for autonomous AI agents, where progress hinges on discovering high-value solutions across complex domains. The driver of this process is effective exploration, however, managing and improving exploration strategies remains a major bottleneck. Current systems face a fundamental dilemma: fixed strategies fail to adapt as search spaces scale, while online policy optimization requires navigating vast meta-search spaces under delayed and expensive feedback over long-horizon rollouts. We introduce Dream-RSI, a framework for scalable and recursively self-improving exploration. A lightweight orchestration layer makes exploration explicit and programmable while leaving the underlying coding agent unchanged. Our key insight is that accumulated discovery history can serve as a replay simulator over the realized search space. By performing dreaming in the replay simulator constructed from historical discovery trees, Dream-RSI secures immediate, low-cost off-policy feedback to evaluate and refine exploration policies without invoking repetitive, expensive online evaluations. The improved policy is subsequently redeployed online to drive further discovery, continuously expanding the simulator pool in a self-improving loop. Across algorithm engineering, mathematical optimization, and GPU kernel engineering, Dream-RSI achieves competitive or improved discovery quality while substantially reducing discovery cost in several settings.

google Google
·
Sep 13 3

Personalized Deep Research: A User-Centric Framework, Dataset, and Hybrid Evaluation for Knowledge Discovery

Deep Research agents driven by LLMs have automated the scholarly discovery pipeline, from planning and query formulation to iterative web exploration. Yet they remain constrained by a static, ``one-size-fits-all'' retrieval paradigm. Current systems fail to adaptively adjust the depth and breadth of exploration based on the user's existing expertise or latent interests, frequently resulting in reports that are either redundant for experts or overly dense for novices. To address this, we introduce Personalized Deep Research (PDR), a framework that integrates dynamic user context into the core retrieval-reasoning loop. Rather than treating personalization as a post-hoc formatting step, PDR unifies user profile modeling with iterative query development, dual-stage (private/public) retrieval, and context-aware synthesis. This allows the system to autonomously align research sub-goals with user intent and optimize the stopping criteria for evidence collection. To facilitate benchmarking, we release the PDR Dataset, covering four realistic user tasks, and propose a hybrid evaluation framework combining lexical metrics with LLM-based judgments to assess factual accuracy and personalization alignment. Experimental results against commercial baselines demonstrate that PDR significantly improves retrieval utility and report relevance, effectively bridging the gap between generic information retrieval and personalized knowledge acquisition. The resource is available to the public at https://github.com/Applied-Machine-Learning-Lab/SIGIR2026_PDR.

  • 9 authors
·
May 10

Automated Discovery Has No Universally Superior Harness

Autonomous discovery systems such as OpenEvolve and TTT-Discover are often used as general-purpose harnesses. However, in practice these are composite systems combining several design choices about archives, parent selection, exploration, and budget allocation into a single recipe. Because discovery runs are expensive and inherently stochastic, existing harnesses are often compared using too few independent trials to distinguish key methodological improvements from run-to-run variance. We systematically decompose OpenEvolve-style evolutionary search and the TTT-Discover search harness into its constituent components and systematically evaluate 30 budget-matched harnesses across 12 model-problem pairs using more than 3.1 million LLM rollouts and repeated-trial statistical analysis. Our results show that discovery harnesses have a generalization problem: No fixed harness is reliably superior across the evaluated model-problem pairs, and variants of OpenEvolve generally underperform simpler alternatives. Thus, harness choice is better viewed as a hyperparameter rather than as a universal recipe, and should be tailored to the specific problem and underlying model. We also find that early discovery progress predicts final performance, and use this property to present a budget-matched adaptive-allocation experiment that starts multiple harnesses, prunes weak partial runs, and reallocates compute to stronger survivors, outperforming both commitment to a randomly sampled fixed harness and a non-adaptive harness ensemble. Together, these results motivate shifting from fixed harness selection to online adaptation guided by early performance. We release all run pools including baseline null distributions for every model-problem pair as reusable statistical infrastructure against for future harness proposals.

  • 5 authors
·
Jul 19

Towards Continual Knowledge Learning of Language Models

Large Language Models (LMs) are known to encode world knowledge in their parameters as they pretrain on a vast amount of web corpus, which is often utilized for performing knowledge-dependent downstream tasks such as question answering, fact-checking, and open dialogue. In real-world scenarios, the world knowledge stored in the LMs can quickly become outdated as the world changes, but it is non-trivial to avoid catastrophic forgetting and reliably acquire new knowledge while preserving invariant knowledge. To push the community towards better maintenance of ever-changing LMs, we formulate a new continual learning (CL) problem called Continual Knowledge Learning (CKL). We construct a new benchmark and metric to quantify the retention of time-invariant world knowledge, the update of outdated knowledge, and the acquisition of new knowledge. We adopt applicable recent methods from literature to create several strong baselines. Through extensive experiments, we find that CKL exhibits unique challenges that are not addressed in previous CL setups, where parameter expansion is necessary to reliably retain and learn knowledge simultaneously. By highlighting the critical causes of knowledge forgetting, we show that CKL is a challenging and important problem that helps us better understand and train ever-changing LMs. The benchmark datasets, evaluation script, and baseline code to reproduce our results are available at https://github.com/joeljang/continual-knowledge-learning.

  • 8 authors
·
Oct 7, 2021

Navigating Ideation Space: Decomposed Conceptual Representations for Positioning Scientific Ideas

Scientific discovery is a cumulative process and requires new ideas to be situated within an ever-expanding landscape of existing knowledge. An emerging and critical challenge is how to identify conceptually relevant prior work from rapidly growing literature, and assess how a new idea differentiates from existing research. Current embedding approaches typically conflate distinct conceptual aspects into single representations and cannot support fine-grained literature retrieval; meanwhile, LLM-based evaluators are subject to sycophancy biases, failing to provide discriminative novelty assessment. To tackle these challenges, we introduce the Ideation Space, a structured representation that decomposes scientific knowledge into three distinct dimensions, i.e., research problem, methodology, and core findings, each learned through contrastive training. This framework enables principled measurement of conceptual distance between ideas, and modeling of ideation transitions that capture the logical connections within a proposed idea. Building upon this representation, we propose a Hierarchical Sub-Space Retrieval framework for efficient, targeted literature retrieval, and a Decomposed Novelty Assessment algorithm that identifies which aspects of an idea are novel. Extensive experiments demonstrate substantial improvements, where our approach achieves Recall@30 of 0.329 (16.7% over baselines), our ideation transition retrieval reaches Hit Rate@30 of 0.643, and novelty assessment attains 0.37 correlation with expert judgments. In summary, our work provides a promising paradigm for future research on accelerating and evaluating scientific discovery.

  • 4 authors
·
Jan 13

Large Discovery Models: Empirically-grounded Model-Based Open-Ended Search

Scientific discovery often involves optimising expensive-to-evaluate objectives over vast, structured, and open-ended hypothesis spaces, such as molecules, protein sequences, and computer programs. Generative models such as large language models (LLMs) provide expressive priors over such spaces, but their likelihoods and self-assessments are unreliable proxies for the objectives and calibrated epistemic uncertainty, especially for novel candidates outside the observed data distribution. We introduce the Large Discovery Model (LDM), an empirically grounded recurrent architecture that couples a generative model with a Bayesian non-parametric reward surrogate model. The generative model proposes and refines candidate designs, while the surrogate predicts their performance and quantifies uncertainty, yielding an uncertainty-aware value that guides candidate generation, refinement, and selection. The discovery memory and the surrogate model are continually updated as each new experimental observation arrives. We evaluate LDM on three scenarios spanning different design modalities and objectives, including neural-network training, antibody design, and molecular optimisation. Compared to LLM-only reflection or traditional statistical search across these domains, LDM achieves a 2.4times greater reduction in validation BPB, an 18.2% relative decrease in binding energy, and more than 60% relative gains in molecular multi-objective performance. These results suggests that LDM could serve as a general-purpose discovery engine for effective search over open-ended hypothesis spaces.

ResearchEVO: An End-to-End Framework for Automated Scientific Discovery and Documentation

An important recurring pattern in scientific breakthroughs is a two-stage process: an initial phase of undirected experimentation that yields an unexpected finding, followed by a retrospective phase that explains why the finding works and situates it within existing theory. We present ResearchEVO, an end-to-end framework that computationally instantiates this discover-then-explain paradigm. The Evolution Phase employs LLM-guided bi-dimensional co-evolution -- simultaneously optimizing both algorithmic logic and overall architecture -- to search the space of code implementations purely by fitness, without requiring any understanding of the solutions it produces. The Writing Phase then takes the best-performing algorithm and autonomously generates a complete, publication-ready research paper through sentence-level retrieval-augmented generation with explicit anti-hallucination verification and automated experiment design. To our knowledge, ResearchEVO is the first system to cover this full pipeline end to end: no prior work jointly performs principled algorithm evolution and literature-grounded scientific documentation. We validate the framework on two cross-disciplinary scientific problems -- Quantum Error Correction using real Google quantum hardware data, and Physics-Informed Neural Networks -- where the Evolution Phase discovered human-interpretable algorithmic mechanisms that had not been previously proposed in the respective domain literatures. In both cases, the Writing Phase autonomously produced compilable LaTeX manuscripts that correctly grounded these blind discoveries in existing theory via RAG, with zero fabricated citations.

  • 7 authors
·
Apr 6

DeepScientist: Advancing Frontier-Pushing Scientific Findings Progressively

While previous AI Scientist systems can generate novel findings, they often lack the focus to produce scientifically valuable contributions that address pressing human-defined challenges. We introduce DeepScientist, a system designed to overcome this by conducting goal-oriented, fully autonomous scientific discovery over month-long timelines. It formalizes discovery as a Bayesian Optimization problem, operationalized through a hierarchical evaluation process consisting of "hypothesize, verify, and analyze". Leveraging a cumulative Findings Memory, this loop intelligently balances the exploration of novel hypotheses with exploitation, selectively promoting the most promising findings to higher-fidelity levels of validation. Consuming over 20,000 GPU hours, the system generated about 5,000 unique scientific ideas and experimentally validated approximately 1100 of them, ultimately surpassing human-designed state-of-the-art (SOTA) methods on three frontier AI tasks by 183.7\%, 1.9\%, and 7.9\%. This work provides the first large-scale evidence of an AI achieving discoveries that progressively surpass human SOTA on scientific tasks, producing valuable findings that genuinely push the frontier of scientific discovery. To facilitate further research into this process, we will open-source all experimental logs and system code at https://github.com/ResearAI/DeepScientist/.

ZeroSearch: Incentivize the Search Capability of LLMs without Searching

Effective information searching is essential for enhancing the reasoning and generation capabilities of large language models (LLMs). Recent research has explored using reinforcement learning (RL) to improve LLMs' search capabilities by interacting with live search engines in real-world environments. While these approaches show promising results, they face two major challenges: (1) Uncontrolled Document Quality: The quality of documents returned by search engines is often unpredictable, introducing noise and instability into the training process. (2) Prohibitively High API Costs: RL training requires frequent rollouts, potentially involving hundreds of thousands of search requests, which incur substantial API expenses and severely constrain scalability. To address these challenges, we introduce ZeroSearch, a reinforcement learning framework that incentivizes the search capabilities of LLMs without interacting with real search engines. Our approach begins with lightweight supervised fine-tuning to transform the LLM into a retrieval module capable of generating both relevant and noisy documents in response to a query. During RL training, we employ a curriculum-based rollout strategy that incrementally degrades the quality of generated documents, progressively eliciting the model's reasoning ability by exposing it to increasingly challenging retrieval scenarios. Extensive experiments demonstrate that ZeroSearch effectively incentivizes the search capabilities of LLMs using a 3B LLM as the retrieval module. Remarkably, a 7B retrieval module achieves comparable performance to the real search engine, while a 14B retrieval module even surpasses it. Furthermore, it generalizes well across both base and instruction-tuned models of various parameter sizes and is compatible with a wide range of RL algorithms.

  • 9 authors
·
May 7, 2025 8

SkillLearnBench: Benchmarking Continual Learning Methods for Agent Skill Generation on Real-World Tasks

Skills have become the de facto way to enable LLM agents to perform complex real-world tasks with customized instructions, workflows, and tools, but how to learn them automatically and effectively remains unclear. We introduce SkillLearnBench, the first benchmark for evaluating continual skill learning methods, comprising 20 verified, skill-dependent tasks across 15 sub-domains derived from a real-world skill taxonomy , evaluated at three levels: skill quality, execution trajectory, and task outcome. Using this benchmark, we evaluate recent continual learning techniques, those leveraging one-shot, self/teacher feedback, and skill creator to generate skills from agent experiences. We find that all continual learning methods improve over the no-skill baseline, yet consistent gains remain elusive: no method leads across all tasks and LLMs, and scaling to stronger LLMs does not reliably help. Continual learning improves tasks with clear, reusable workflows but struggles on open-ended tasks, and using stronger LLM backbones does not consistently produce better skills. Our analysis also revealed that multiple iterations in continual learning facilitate genuine improvement via external feedback, whereas self-feedback alone induces recursive drift. Our data and code are open-source at https://github.com/cxcscmu/SkillLearnBench to enable further studies of automatic skill generation and continual learning techniques.

IDEAgent: Agentic Quality-Diversity Search for Research Idea Generation

Large Language Models (LLMs) have significantly automated the process of scientific discovery over the past few years. However, existing systems share one core limitation: they generate and optimize ideas independently for either Quality or Diversity. This often leads to the generation of ideas in close proximity to one another or to a large set of trivial, unsound, or unclear concepts. In this work, we instead argue that research ideation should be treated as a conjunction of both objectives and framed as a Quality-Diversity (QD) search. In line with this perspective, we introduce IDEAgent, a multi-agent framework that manages the evolution of ideas through lineages. We jointly drive Quality using multi-objective feedback for dedicated repair and refinement, while Diversity is achieved through lightweight sequential memory and explicit comparison against completed ideas, their historical ancestors, and rejected proposals. To systematically evaluate this QD conjunction, we develop Yield, a joint metric that computes the largest set of mutually diverse ideas that satisfy a predetermined quality threshold. Finally, through evaluations across 32 topics spanning 8 domains of Computer Science, we show that IDEAgent outperforms the best baseline by 3.89x on Yield, while achieving non-zero Yield on 8x more topics. We further corroborate these findings through an analysis of quality improvements, showing that repair and refinement are crucial for building logical rigor and clarity while preserving non-obviousness. To encourage future research on QD-search-based ideation, we open-source IDEAgent at https://github.com/declare-lab/IDEAgent.

Overcoming Growth-Induced Forgetting in Task-Agnostic Continual Learning

In continual learning (CL), model growth enhances adaptability to new data. However, when model growth is applied improperly, especially in task-agnostic CL, where the entire grown model is used for inference, it can lead to severe degradation of learned knowledge, a problem we term growth-induced forgetting. Most existing methods that adopt model growth to improve adaptability often overlook the forgetting issue, resulting in compromised knowledge retention, making them unsuitable for task-agnostic settings. To promote both adaptability and knowledge retention with model growth, we identify the key: gradient and parameter sparsity. Introducing SparseGrow, which increases gradient sparsity through layer expansion and gradient gating to enable focused updates on parameters while preserving critical parameters, thus inhibiting forgetting. Moreover, it promotes parameter sparsity with sparse initialization and training, aiming at better control of model plasticity, improving adaptability over new data. Extensive experiments across diverse datasets, task-agnostic settings, and a large number of tasks demonstrate the necessity of controlled layer expansion and validate the effectiveness of SparseGrow in achieving high adaptability while minimizing forgetting in continual learning. By enabling model growth with sparsified gradients and parameters, SparseGrow paves the way for building scalable lifelong learning systems capable of continual adaptation with better knowledge retention.

  • 7 authors
·
Dec 21, 2025

Build Your Personalized Research Group: A Multiagent Framework for Continual and Interactive Science Automation

The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that cannot adapt to intermediate findings, and inadequate context management that hinders long-horizon research. We present freephdlabor, an open-source multiagent framework featuring fully dynamic workflows determined by real-time agent reasoning and a \textit{modular architecture} enabling seamless customization -- users can modify, add, or remove agents to address domain-specific requirements. The framework provides comprehensive infrastructure including automatic context compaction, workspace-based communication to prevent information degradation, memory persistence across sessions, and non-blocking human intervention mechanisms. These features collectively transform automated research from isolated, single-run attempts into continual research programs that build systematically on prior explorations and incorporate human feedback. By providing both the architectural principles and practical implementation for building customizable co-scientist systems, this work aims to facilitate broader adoption of automated research across scientific domains, enabling practitioners to deploy interactive multiagent systems that autonomously conduct end-to-end research -- from ideation through experimentation to publication-ready manuscripts.

  • 7 authors
·
Oct 17, 2025 5

LibContinual: A Comprehensive Library towards Realistic Continual Learning

A fundamental challenge in Continual Learning (CL) is catastrophic forgetting, where adapting to new tasks degrades the performance on previous ones. While the field has evolved with diverse methods, this rapid surge in diverse methodologies has culminated in a fragmented research landscape. The lack of a unified framework, including inconsistent implementations, conflicting dependencies, and varying evaluation protocols, makes fair comparison and reproducible research increasingly difficult. To address this challenge, we propose LibContinual, a comprehensive and reproducible library designed to serve as a foundational platform for realistic CL. Built upon a high-cohesion, low-coupling modular architecture, LibContinual integrates 19 representative algorithms across five major methodological categories, providing a standardized execution environment. Meanwhile, leveraging this unified framework, we systematically identify and investigate three implicit assumptions prevalent in mainstream evaluation: (1) offline data accessibility, (2) unregulated memory resources, and (3) intra-task semantic homogeneity. We argue that these assumptions often overestimate the real-world applicability of CL methods. Through our comprehensive analysis using strict online CL settings, a novel unified memory budget protocol, and a proposed category-randomized setting, we reveal significant performance drops in many representative CL methods when subjected to these real-world constraints. Our study underscores the necessity of resource-aware and semantically robust CL strategies, and offers LibContinual as a foundational toolkit for future research in realistic continual learning. The source code is available from https://github.com/RL-VIG/LibContinual{https://github.com/RL-VIG/LibContinual}.

  • 10 authors
·
Dec 25, 2025

SmartSearch: Process Reward-Guided Query Refinement for Search Agents

Large language model (LLM)-based search agents have proven promising for addressing knowledge-intensive problems by incorporating information retrieval capabilities. Existing works largely focus on optimizing the reasoning paradigms of search agents, yet the quality of intermediate search queries during reasoning remains overlooked. As a result, the generated queries often remain inaccurate, leading to unexpected retrieval results and ultimately limiting search agents' overall effectiveness. To mitigate this issue, we introduce SmartSearch, a framework built upon two key mechanisms: (1) Process rewards, which provide fine-grained supervision for the quality of each intermediate search query through Dual-Level Credit Assessment. (2) Query refinement, which promotes the optimization of query generation by selectively refining low-quality search queries and regenerating subsequent search rounds based on these refinements. To enable the search agent to progressively internalize the ability to improve query quality under the guidance of process rewards, we design a three-stage curriculum learning framework. This framework guides the agent through a progression from imitation, to alignment, and ultimately to generalization. Experimental results show that SmartSearch consistently surpasses existing baselines, and additional quantitative analyses further confirm its significant gains in both search efficiency and query quality. The code is available at https://github.com/MYVAE/SmartSearch.

  • 3 authors
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Jan 8 3

UltraHorizon: Benchmarking Agent Capabilities in Ultra Long-Horizon Scenarios

Autonomous agents have recently achieved remarkable progress across diverse domains, yet most evaluations focus on short-horizon, fully observable tasks. In contrast, many critical real-world tasks, such as large-scale software development, commercial investment, and scientific discovery, unfold in long-horizon and partially observable scenarios where success hinges on sustained reasoning, planning, memory management, and tool use. Existing benchmarks rarely capture these long-horizon challenges, leaving a gap in systematic evaluation. To bridge this gap, we introduce UltraHorizon a novel benchmark that measures the foundational capabilities essential for complex real-world challenges. We use exploration as a unifying task across three distinct environments to validate these core competencies. Agents are designed in long-horizon discovery tasks where they must iteratively uncover hidden rules through sustained reasoning, planning, memory and tools management, and interaction with environments. Under the heaviest scale setting, trajectories average 200k+ tokens and 400+ tool calls, whereas in standard configurations they still exceed 35k tokens and involve more than 60 tool calls on average. Our extensive experiments reveal that LLM-agents consistently underperform in these settings, whereas human participants achieve higher scores, underscoring a persistent gap in agents' long-horizon abilities. We also observe that simple scaling fails in our task. To better illustrate the failure of agents, we conduct an in-depth analysis of collected trajectories. We identify eight types of errors and attribute them to two primary causes: in-context locking and functional fundamental capability gaps. https://github.com/StarDewXXX/UltraHorizon{Our code will be available here.}

  • 18 authors
·
Sep 25, 2025 2

Idea2Story: An Automated Pipeline for Transforming Research Concepts into Complete Scientific Narratives

Autonomous scientific discovery with large language model (LLM)-based agents has recently made substantial progress, demonstrating the ability to automate end-to-end research workflows. However, existing systems largely rely on runtime-centric execution paradigms, repeatedly reading, summarizing, and reasoning over large volumes of scientific literature online. This on-the-spot computation strategy incurs high computational cost, suffers from context window limitations, and often leads to brittle reasoning and hallucination. We propose Idea2Story, a pre-computation-driven framework for autonomous scientific discovery that shifts literature understanding from online reasoning to offline knowledge construction. Idea2Story continuously collects peer-reviewed papers together with their review feedback, extracts core methodological units, composes reusable research patterns, and organizes them into a structured methodological knowledge graph. At runtime, underspecified user research intents are aligned to established research paradigms, enabling efficient retrieval and reuse of high-quality research patterns instead of open-ended generation and trial-and-error. By grounding research planning and execution in a pre-built knowledge graph, Idea2Story alleviates the context window bottleneck of LLMs and substantially reduces repeated runtime reasoning over literature. We conduct qualitative analyses and preliminary empirical studies demonstrating that Idea2Story can generate coherent, methodologically grounded, and novel research patterns, and can produce several high-quality research demonstrations in an end-to-end setting. These results suggest that offline knowledge construction provides a practical and scalable foundation for reliable autonomous scientific discovery.

AgentAlphaAGI AgentAlpha
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Jan 28 2

AlphaResearch: Accelerating New Algorithm Discovery with Language Models

Large language models have made significant progress in complex but easy-to-verify problems, yet they still struggle with discovering the unknown. In this paper, we present AlphaResearch, an autonomous research agent designed to discover new algorithms on open-ended problems. To synergize the feasibility and innovation of the discovery process, we construct a novel dual research environment by combining the execution-based verify and simulated real-world peer review environment. AlphaResearch discovers new algorithm by iteratively running the following steps: (1) propose new ideas (2) verify the ideas in the dual research environment (3) optimize the research proposals for better performance. To promote a transparent evaluation process, we construct AlphaResearchComp, a new evaluation benchmark that includes an eight open-ended algorithmic problems competition, with each problem carefully curated and verified through executable pipelines, objective metrics, and reproducibility checks. AlphaResearch gets a 2/8 win rate in head-to-head comparison with human researchers, demonstrate the possibility of accelerating algorithm discovery with LLMs. Notably, the algorithm discovered by AlphaResearch on the ``packing circles'' problem achieves the best-of-known performance, surpassing the results of human researchers and strong baselines from recent work (e.g., AlphaEvolve). Additionally, we conduct a comprehensive analysis of the remaining challenges of the 6/8 failure cases, providing valuable insights for future research.

  • 6 authors
·
Nov 11, 2025 2

Beyond Not-Forgetting: Continual Learning with Backward Knowledge Transfer

By learning a sequence of tasks continually, an agent in continual learning (CL) can improve the learning performance of both a new task and `old' tasks by leveraging the forward knowledge transfer and the backward knowledge transfer, respectively. However, most existing CL methods focus on addressing catastrophic forgetting in neural networks by minimizing the modification of the learnt model for old tasks. This inevitably limits the backward knowledge transfer from the new task to the old tasks, because judicious model updates could possibly improve the learning performance of the old tasks as well. To tackle this problem, we first theoretically analyze the conditions under which updating the learnt model of old tasks could be beneficial for CL and also lead to backward knowledge transfer, based on the gradient projection onto the input subspaces of old tasks. Building on the theoretical analysis, we next develop a ContinUal learning method with Backward knowlEdge tRansfer (CUBER), for a fixed capacity neural network without data replay. In particular, CUBER first characterizes the task correlation to identify the positively correlated old tasks in a layer-wise manner, and then selectively modifies the learnt model of the old tasks when learning the new task. Experimental studies show that CUBER can even achieve positive backward knowledge transfer on several existing CL benchmarks for the first time without data replay, where the related baselines still suffer from catastrophic forgetting (negative backward knowledge transfer). The superior performance of CUBER on the backward knowledge transfer also leads to higher accuracy accordingly.

  • 4 authors
·
Nov 1, 2022

CHEEM: Continual Learning by Reuse, New, Adapt and Skip -- A Hierarchical Exploration-Exploitation Approach

To effectively manage the complexities of real-world dynamic environments, continual learning must incrementally acquire, update, and accumulate knowledge from a stream of tasks of different nature without suffering from catastrophic forgetting of prior knowledge. While this capability is innate to human cognition, it remains a significant challenge for modern deep learning systems. At the heart of this challenge lies the stability-plasticity dilemma: the need to balance leveraging prior knowledge, integrating novel information, and allocating model capacity adaptively based on task complexity and synergy. In this paper, we propose a novel exemplar-free class-incremental continual learning (ExfCCL) framework that addresses these issues through a Hierarchical Exploration-Exploitation (HEE) approach. The core of our method is a HEE-guided efficient neural architecture search (HEE-NAS) that enables a learning-to-adapt backbone via four primitive operations - reuse, new, adapt, and skip - thereby serving as an internal memory that dynamically updates selected components across streaming tasks. To address the task ID inference problem in ExfCCL, we exploit an external memory of task centroids proposed in the prior art. We term our method CHEEM (Continual Hierarchical-Exploration-Exploitation Memory). CHEEM is evaluated on the challenging MTIL and VDD benchmarks using both Tiny and Base Vision Transformers and a proposed holistic Figure-of-Merit (FoM) metric. It significantly outperforms state-of-the-art prompting-based continual learning methods, closely approaching full fine-tuning upper bounds. Furthermore, it learns adaptive model structures tailored to individual tasks in a semantically meaningful way. Our code is available at https://github.com/savadikarc/cheem .

  • 3 authors
·
Mar 14, 2023

Evaluating Large Language Models in Scientific Discovery

Large language models (LLMs) are increasingly applied to scientific research, yet prevailing science benchmarks probe decontextualized knowledge and overlook the iterative reasoning, hypothesis generation, and observation interpretation that drive scientific discovery. We introduce a scenario-grounded benchmark that evaluates LLMs across biology, chemistry, materials, and physics, where domain experts define research projects of genuine interest and decompose them into modular research scenarios from which vetted questions are sampled. The framework assesses models at two levels: (i) question-level accuracy on scenario-tied items and (ii) project-level performance, where models must propose testable hypotheses, design simulations or experiments, and interpret results. Applying this two-phase scientific discovery evaluation (SDE) framework to state-of-the-art LLMs reveals a consistent performance gap relative to general science benchmarks, diminishing return of scaling up model sizes and reasoning, and systematic weaknesses shared across top-tier models from different providers. Large performance variation in research scenarios leads to changing choices of the best performing model on scientific discovery projects evaluated, suggesting all current LLMs are distant to general scientific "superintelligence". Nevertheless, LLMs already demonstrate promise in a great variety of scientific discovery projects, including cases where constituent scenario scores are low, highlighting the role of guided exploration and serendipity in discovery. This SDE framework offers a reproducible benchmark for discovery-relevant evaluation of LLMs and charts practical paths to advance their development toward scientific discovery.

  • 56 authors
·
Dec 17, 2025

Spacer: Towards Engineered Scientific Inspiration

Recent advances in LLMs have made automated scientific research the next frontline in the path to artificial superintelligence. However, these systems are bound either to tasks of narrow scope or the limited creative capabilities of LLMs. We propose Spacer, a scientific discovery system that develops creative and factually grounded concepts without external intervention. Spacer attempts to achieve this via 'deliberate decontextualization,' an approach that disassembles information into atomic units - keywords - and draws creativity from unexplored connections between them. Spacer consists of (i) Nuri, an inspiration engine that builds keyword sets, and (ii) the Manifesting Pipeline that refines these sets into elaborate scientific statements. Nuri extracts novel, high-potential keyword sets from a keyword graph built with 180,000 academic publications in biological fields. The Manifesting Pipeline finds links between keywords, analyzes their logical structure, validates their plausibility, and ultimately drafts original scientific concepts. According to our experiments, the evaluation metric of Nuri accurately classifies high-impact publications with an AUROC score of 0.737. Our Manifesting Pipeline also successfully reconstructs core concepts from the latest top-journal articles solely from their keyword sets. An LLM-based scoring system estimates that this reconstruction was sound for over 85% of the cases. Finally, our embedding space analysis shows that outputs from Spacer are significantly more similar to leading publications compared with those from SOTA LLMs.

  • 16 authors
·
Aug 25, 2025 2

RSIBench-Data: Benchmarking Data-Centric Research for Recursive Self-Improvement

Recursive self-improvement requires turning evidence of model failures into better models. Data-centric post-training research entails diagnosing capability gaps, designing and validating training-data strategies, and learning from checkpoint feedback. Can LLM agents automate this loop? Existing benchmarks entangle research decisions with optimization, serving, evaluation, and systems implementation, obscuring agents' research capability. We introduce RSIBench-Data, a controlled benchmark of LLM agents as data-centric researchers with a fixed post-training stack. Agents iteratively revise training-data strategies for a fixed target model; training and serving use Tinker-backed services, official evaluation runs through Harbor and E2B sandboxes, and budgets are fixed across agents. We evaluate four frontier agents on six benchmarks across software engineering, terminal use, scientific question answering, and mathematics. Agents demonstrate core data-centric research capabilities: in 58.33\% of settings, they improve upon the first valid attempt by refining strategies from feedback. However, improvement is inconsistent. Among searches continuing after the best observed score, 78.26\% end with a lower-scoring final attempt, while the rest only recover the same peak. A strong candidate may therefore appear early or midway through a run even as later revisions fail. Trajectory analysis identifies four patterns in stronger runs: accurate hypotheses, validation-grounded supervision, behavior-aligned data, and preservation of strong checkpoints. These findings suggest that current agents can make useful data-centric discoveries but cannot yet translate feedback into consistent improvements. RSIBench-Data provides a measurable, auditable testbed for the research capabilities required for recursive self-improvement. We open-source our code at https://github.com/evolvent-ai/RSIBench-Data.

  • 7 authors
·
Jul 27

Learning to Generate Research Idea with Dynamic Control

The rapid advancements in large language models (LLMs) have demonstrated their potential to accelerate scientific discovery, particularly in automating the process of research ideation. LLM-based systems have shown promise in generating hypotheses and research ideas. However, current approaches predominantly rely on prompting-based pre-trained models, limiting their ability to optimize generated content effectively. Moreover, they also lack the capability to deal with the complex interdependence and inherent restrictions among novelty, feasibility, and effectiveness, which remains challenging due to the inherent trade-offs among these dimensions, such as the innovation-feasibility conflict. To address these limitations, we for the first time propose fine-tuning LLMs to be better idea proposers and introduce a novel framework that employs a two-stage approach combining Supervised Fine-Tuning (SFT) and controllable Reinforcement Learning (RL). In the SFT stage, the model learns foundational patterns from pairs of research papers and follow-up ideas. In the RL stage, multi-dimensional reward modeling, guided by fine-grained feedback, evaluates and optimizes the generated ideas across key metrics. Dimensional controllers enable dynamic adjustment of generation, while a sentence-level decoder ensures context-aware emphasis during inference. Our framework provides a balanced approach to research ideation, achieving high-quality outcomes by dynamically navigating the trade-offs among novelty, feasibility, and effectiveness.

  • 5 authors
·
Dec 19, 2024

SearchOS-V1: Towards Robust Open-Domain Information-Seeking Agent Collaboration

Recent advances in Tool-Integrated Large Language Models have made web search a core capability of information-seeking agents. However, as interaction histories grow, agents increasingly struggle to track task progress. When search attempts fail to yield useful evidence, current single- and multi-agent systems can become trapped in repetitive loops, wasting search budgets and ultimately compromising the quality and completeness of the final output. We introduce SearchOS, a system-level multi-agent framework that turns fragile, implicit search progress into explicit, persistent, and shared state. First, we formulate open-domain information seeking as relational schema completion with grounded citations, where agents discover entities, populate attributes across linked tables, and anchor each value to source evidence. Then we design Search-Oriented Context Management (SOCM), which externalizes the evolving state into Frontier Task, an Evidence Graph, a Coverage Map, and Failure Memory. Built on SOCM, SearchOS applies a pipeline-parallel scheduling mechanism that overlaps the execution of sub-agents and continuously refills freed slots with tasks targeting unresolved coverage gaps to improve utilization and throughput. To schedule and control the execution of search agents, SearchOS introduces a Search Tool Middleware Harness that intercepts model and tool interactions to record grounded evidence and react to stalls or budget exhaustion, and provides a reusable hierarchical skill system comprising strategy and access skills to augment the agents' search process and avoid repeating failed search patterns across runs. On WideSearch and GISA, SearchOS leads all metrics among the evaluated single- and multi-agent baselines, paving the way toward robust information-seeking collaboration.

antgroup Ant Group
·
Jul 15 1

Omni-SimpleMem: Autoresearch-Guided Discovery of Lifelong Multimodal Agent Memory

AI agents increasingly operate over extended time horizons, yet their ability to retain, organize, and recall multimodal experiences remains a critical bottleneck. Building effective lifelong memory requires navigating a vast design space spanning architecture, retrieval strategies, prompt engineering, and data pipelines; this space is too large and interconnected for manual exploration or traditional AutoML to explore effectively. We deploy an autonomous research pipeline to discover Omni-SimpleMem, a unified multimodal memory framework for lifelong AI agents. Starting from a naïve baseline (F1=0.117 on LoCoMo), the pipeline autonomously executes {sim}50 experiments across two benchmarks, diagnosing failure modes, proposing architectural modifications, and repairing data pipeline bugs, all without human intervention in the inner loop. The resulting system achieves state-of-the-art on both benchmarks, improving F1 by +411% on LoCoMo (0.117to0.598) and +214% on Mem-Gallery (0.254to0.797) relative to the initial configurations. Critically, the most impactful discoveries are not hyperparameter adjustments: bug fixes (+175%), architectural changes (+44%), and prompt engineering (+188% on specific categories) each individually exceed the cumulative contribution of all hyperparameter tuning, demonstrating capabilities fundamentally beyond the reach of traditional AutoML. We provide a taxonomy of six discovery types and identify four properties that make multimodal memory particularly suited for autoresearch, offering guidance for applying autonomous research pipelines to other AI system domains. Code is available at this https://github.com/aiming-lab/SimpleMem.

AutoLab: Can Frontier Models Solve Long-Horizon Auto Research and Engineering Tasks?

Scientific and engineering progress is fundamentally a long-horizon iterative process: proposing changes, running experiments, measuring outcomes, and continuously refining artifacts. Yet existing benchmarks for frontier models primarily evaluate either single-turn responses or short-horizon agent trajectories, failing to capture the challenges of sustained iterative improvement over extended time horizons. To address this gap, we introduce AutoLab, a new benchmark for ultra long-horizon closed-loop optimization. AutoLab consists of 36 realistic, expert-curated tasks spanning four diverse domains: system optimization, puzzle & challenge, model development, and CUDA kernel optimization. Each task begins with a correct but deliberately suboptimal baseline and challenges agents to improve it within a strict wall-clock budget. Evaluating 17 state-of-the-art models reveals the dominant predictor of success is not the quality of an agent's initial attempt, but its persistence in repeatedly benchmarking, editing, and incorporating empirical feedback. While claude-opus-4.6 exhibits strong long-horizon optimization capabilities, most frontier models, including several proprietary ones, either terminate prematurely or exhaust their budgets with minimal progress. These results underscore the importance of time awareness and persistent iteration in autonomous agents. We open-source the full benchmark, evaluation harness, and task artifacts, to accelerate research toward truly capable long-horizon agents.

  • 19 authors
·
Jun 2

Challenging Common Assumptions about Catastrophic Forgetting

Building learning agents that can progressively learn and accumulate knowledge is the core goal of the continual learning (CL) research field. Unfortunately, training a model on new data usually compromises the performance on past data. In the CL literature, this effect is referred to as catastrophic forgetting (CF). CF has been largely studied, and a plethora of methods have been proposed to address it on short sequences of non-overlapping tasks. In such setups, CF always leads to a quick and significant drop in performance in past tasks. Nevertheless, despite CF, recent work showed that SGD training on linear models accumulates knowledge in a CL regression setup. This phenomenon becomes especially visible when tasks reoccur. We might then wonder if DNNs trained with SGD or any standard gradient-based optimization accumulate knowledge in such a way. Such phenomena would have interesting consequences for applying DNNs to real continual scenarios. Indeed, standard gradient-based optimization methods are significantly less computationally expensive than existing CL algorithms. In this paper, we study the progressive knowledge accumulation (KA) in DNNs trained with gradient-based algorithms in long sequences of tasks with data re-occurrence. We propose a new framework, SCoLe (Scaling Continual Learning), to investigate KA and discover that catastrophic forgetting has a limited effect on DNNs trained with SGD. When trained on long sequences with data sparsely re-occurring, the overall accuracy improves, which might be counter-intuitive given the CF phenomenon. We empirically investigate KA in DNNs under various data occurrence frequencies and propose simple and scalable strategies to increase knowledge accumulation in DNNs.

  • 7 authors
·
Jul 10, 2022

SLCA: Slow Learner with Classifier Alignment for Continual Learning on a Pre-trained Model

The goal of continual learning is to improve the performance of recognition models in learning sequentially arrived data. Although most existing works are established on the premise of learning from scratch, growing efforts have been devoted to incorporating the benefits of pre-training. However, how to adaptively exploit the pre-trained knowledge for each incremental task while maintaining its generalizability remains an open question. In this work, we present an extensive analysis for continual learning on a pre-trained model (CLPM), and attribute the key challenge to a progressive overfitting problem. Observing that selectively reducing the learning rate can almost resolve this issue in the representation layer, we propose a simple but extremely effective approach named Slow Learner with Classifier Alignment (SLCA), which further improves the classification layer by modeling the class-wise distributions and aligning the classification layers in a post-hoc fashion. Across a variety of scenarios, our proposal provides substantial improvements for CLPM (e.g., up to 49.76%, 50.05%, 44.69% and 40.16% on Split CIFAR-100, Split ImageNet-R, Split CUB-200 and Split Cars-196, respectively), and thus outperforms state-of-the-art approaches by a large margin. Based on such a strong baseline, critical factors and promising directions are analyzed in-depth to facilitate subsequent research. Code has been made available at: https://github.com/GengDavid/SLCA.

  • 5 authors
·
Mar 9, 2023

A Definition of Continual Reinforcement Learning

In a standard view of the reinforcement learning problem, an agent's goal is to efficiently identify a policy that maximizes long-term reward. However, this perspective is based on a restricted view of learning as finding a solution, rather than treating learning as endless adaptation. In contrast, continual reinforcement learning refers to the setting in which the best agents never stop learning. Despite the importance of continual reinforcement learning, the community lacks a simple definition of the problem that highlights its commitments and makes its primary concepts precise and clear. To this end, this paper is dedicated to carefully defining the continual reinforcement learning problem. We formalize the notion of agents that "never stop learning" through a new mathematical language for analyzing and cataloging agents. Using this new language, we define a continual learning agent as one that can be understood as carrying out an implicit search process indefinitely, and continual reinforcement learning as the setting in which the best agents are all continual learning agents. We provide two motivating examples, illustrating that traditional views of multi-task reinforcement learning and continual supervised learning are special cases of our definition. Collectively, these definitions and perspectives formalize many intuitive concepts at the heart of learning, and open new research pathways surrounding continual learning agents.

  • 6 authors
·
Jul 20, 2023

WebLeaper: Empowering Efficiency and Efficacy in WebAgent via Enabling Info-Rich Seeking

Large Language Model (LLM)-based agents have emerged as a transformative approach for open-ended problem solving, with information seeking (IS) being a core capability that enables autonomous reasoning and decision-making. While prior research has largely focused on improving retrieval depth, we observe that current IS agents often suffer from low search efficiency, which in turn constrains overall performance. A key factor underlying this inefficiency is the sparsity of target entities in training tasks, which limits opportunities for agents to learn and generalize efficient search behaviors. To address these challenges, we propose WebLeaper, a framework for constructing high-coverage IS tasks and generating efficient solution trajectories. We formulate IS as a tree-structured reasoning problem, enabling a substantially larger set of target entities to be embedded within a constrained context. Leveraging curated Wikipedia tables, we propose three variants for synthesizing IS tasks, Basic, Union, and Reverse-Union, to systematically increase both IS efficiency and efficacy. Finally, we curate training trajectories by retaining only those that are simultaneously accurate and efficient, ensuring that the model is optimized for both correctness and search performance. Extensive experiments on both basic and comprehensive settings, conducted on five IS benchmarks, BrowserComp, GAIA, xbench-DeepSearch, WideSearch, and Seal-0, demonstrate that our method consistently achieves improvements in both effectiveness and efficiency over strong baselines.

AlibabaTongyiLab TongyiLab
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Oct 28, 2025 2

DSI++: Updating Transformer Memory with New Documents

Differentiable Search Indices (DSIs) encode a corpus of documents in model parameters and use the same model to answer user queries directly. Despite the strong performance of DSI models, deploying them in situations where the corpus changes over time is computationally expensive because reindexing the corpus requires re-training the model. In this work, we introduce DSI++, a continual learning challenge for DSI to incrementally index new documents while being able to answer queries related to both previously and newly indexed documents. Across different model scales and document identifier representations, we show that continual indexing of new documents leads to considerable forgetting of previously indexed documents. We also hypothesize and verify that the model experiences forgetting events during training, leading to unstable learning. To mitigate these issues, we investigate two approaches. The first focuses on modifying the training dynamics. Flatter minima implicitly alleviate forgetting, so we optimize for flatter loss basins and show that the model stably memorizes more documents (+12%). Next, we introduce a generative memory to sample pseudo-queries for documents and supplement them during continual indexing to prevent forgetting for the retrieval task. Extensive experiments on novel continual indexing benchmarks based on Natural Questions (NQ) and MS MARCO demonstrate that our proposed solution mitigates forgetting significantly. Concretely, it improves the average Hits@10 by +21.1% over competitive baselines for NQ and requires 6 times fewer model updates compared to re-training the DSI model for incrementally indexing five corpora in a sequence.

  • 9 authors
·
Dec 19, 2022

IterResearch: Rethinking Long-Horizon Agents via Markovian State Reconstruction

Recent advances in deep-research agents have shown promise for autonomous knowledge construction through dynamic reasoning over external sources. However, existing approaches rely on a mono-contextual paradigm that accumulates all information in a single, expanding context window, leading to context suffocation and noise contamination that limit their effectiveness on long-horizon tasks. We introduce IterResearch, a novel iterative deep-research paradigm that reformulates long-horizon research as a Markov Decision Process with strategic workspace reconstruction. By maintaining an evolving report as memory and periodically synthesizing insights, our approach preserves consistent reasoning capacity across arbitrary exploration depths. We further develop Efficiency-Aware Policy Optimization (EAPO), a reinforcement learning framework that incentivizes efficient exploration through geometric reward discounting and enables stable distributed training via adaptive downsampling. Extensive experiments demonstrate that IterResearch achieves substantial improvements over existing open-source agents with average +14.5pp across six benchmarks and narrows the gap with frontier proprietary systems. Remarkably, our paradigm exhibits unprecedented interaction scaling, extending to 2048 interactions with dramatic performance gains (from 3.5\% to 42.5\%), and serves as an effective prompting strategy, improving frontier models by up to 19.2pp over ReAct on long-horizon tasks. These findings position IterResearch as a versatile solution for long-horizon reasoning, effective both as a trained agent and as a prompting paradigm for frontier models.

  • 16 authors
·
Nov 10, 2025 11

OpenSeeker: Democratizing Frontier Search Agents by Fully Open-Sourcing Training Data

Deep search capabilities have become an indispensable competency for frontier Large Language Model (LLM) agents, yet the development of high-performance search agents remains dominated by industrial giants due to a lack of transparent, high-quality training data. This persistent data scarcity has fundamentally hindered the progress of the broader research community in developing and innovating within this domain. To bridge this gap, we introduce OpenSeeker, the first fully open-source search agent (i.e., model and data) that achieves frontier-level performance through two core technical innovations: (1) Fact-grounded scalable controllable QA synthesis, which reverse-engineers the web graph via topological expansion and entity obfuscation to generate complex, multi-hop reasoning tasks with controllable coverage and complexity. (2) Denoised trajectory synthesis, which employs a retrospective summarization mechanism to denoise the trajectory, therefore promoting the teacher LLMs to generate high-quality actions. Experimental results demonstrate that OpenSeeker, trained (a single training run) on only 11.7k synthesized samples, achieves state-of-the-art performance across multiple benchmarks including BrowseComp, BrowseComp-ZH, xbench-DeepSearch, and WideSearch. Notably, trained with simple SFT, OpenSeeker significantly outperforms the second-best fully open-source agent DeepDive (e.g., 29.5% v.s. 15.3% on BrowseComp), and even surpasses industrial competitors such as Tongyi DeepResearch (trained via extensive continual pre-training, SFT, and RL) on BrowseComp-ZH (48.4% v.s. 46.7%). We fully open-source the complete training dataset and the model weights to democratize frontier search agent research and foster a more transparent, collaborative ecosystem.

OpenSeeker OpenSeeker
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Mar 16 6

O1 Replication Journey: A Strategic Progress Report -- Part 1

This paper introduces a pioneering approach to artificial intelligence research, embodied in our O1 Replication Journey. In response to the announcement of OpenAI's groundbreaking O1 model, we embark on a transparent, real-time exploration to replicate its capabilities while reimagining the process of conducting and communicating AI research. Our methodology addresses critical challenges in modern AI research, including the insularity of prolonged team-based projects, delayed information sharing, and the lack of recognition for diverse contributions. By providing comprehensive, real-time documentation of our replication efforts, including both successes and failures, we aim to foster open science, accelerate collective advancement, and lay the groundwork for AI-driven scientific discovery. Our research progress report diverges significantly from traditional research papers, offering continuous updates, full process transparency, and active community engagement throughout the research journey. Technologically, we proposed the journey learning paradigm, which encourages models to learn not just shortcuts, but the complete exploration process, including trial and error, reflection, and backtracking. With only 327 training samples and without any additional tricks, journey learning outperformed conventional supervised learning by over 8\% on the MATH dataset, demonstrating its extremely powerful potential. We believe this to be the most crucial component of O1 technology that we have successfully decoded. We share valuable resources including technical hypotheses and insights, cognitive exploration maps, custom-developed tools, etc at https://github.com/GAIR-NLP/O1-Journey.

  • 11 authors
·
Oct 8, 2024

Towards Lifelong Learning of Large Language Models: A Survey

As the applications of large language models (LLMs) expand across diverse fields, the ability of these models to adapt to ongoing changes in data, tasks, and user preferences becomes crucial. Traditional training methods, relying on static datasets, are increasingly inadequate for coping with the dynamic nature of real-world information. Lifelong learning, also known as continual or incremental learning, addresses this challenge by enabling LLMs to learn continuously and adaptively over their operational lifetime, integrating new knowledge while retaining previously learned information and preventing catastrophic forgetting. This survey delves into the sophisticated landscape of lifelong learning, categorizing strategies into two primary groups: Internal Knowledge and External Knowledge. Internal Knowledge includes continual pretraining and continual finetuning, each enhancing the adaptability of LLMs in various scenarios. External Knowledge encompasses retrieval-based and tool-based lifelong learning, leveraging external data sources and computational tools to extend the model's capabilities without modifying core parameters. The key contributions of our survey are: (1) Introducing a novel taxonomy categorizing the extensive literature of lifelong learning into 12 scenarios; (2) Identifying common techniques across all lifelong learning scenarios and classifying existing literature into various technique groups within each scenario; (3) Highlighting emerging techniques such as model expansion and data selection, which were less explored in the pre-LLM era. Through a detailed examination of these groups and their respective categories, this survey aims to enhance the adaptability, reliability, and overall performance of LLMs in real-world applications.

  • 4 authors
·
Jun 10, 2024

Continual Learning with Dynamic Sparse Training: Exploring Algorithms for Effective Model Updates

Continual learning (CL) refers to the ability of an intelligent system to sequentially acquire and retain knowledge from a stream of data with as little computational overhead as possible. To this end; regularization, replay, architecture, and parameter isolation approaches were introduced to the literature. Parameter isolation using a sparse network which enables to allocate distinct parts of the neural network to different tasks and also allows to share of parameters between tasks if they are similar. Dynamic Sparse Training (DST) is a prominent way to find these sparse networks and isolate them for each task. This paper is the first empirical study investigating the effect of different DST components under the CL paradigm to fill a critical research gap and shed light on the optimal configuration of DST for CL if it exists. Therefore, we perform a comprehensive study in which we investigate various DST components to find the best topology per task on well-known CIFAR100 and miniImageNet benchmarks in a task-incremental CL setup since our primary focus is to evaluate the performance of various DST criteria, rather than the process of mask selection. We found that, at a low sparsity level, Erdos-Renyi Kernel (ERK) initialization utilizes the backbone more efficiently and allows to effectively learn increments of tasks. At a high sparsity level, however, uniform initialization demonstrates more reliable and robust performance. In terms of growth strategy; performance is dependent on the defined initialization strategy, and the extent of sparsity. Finally, adaptivity within DST components is a promising way for better continual learners.

  • 5 authors
·
Aug 28, 2023

Rethinking Scientific Discovery in the Agentic Era

Artificial intelligence has advanced scientific discovery, but most AI4Science systems remain fragmented tools that rely on humans to coordinate problem formulation, literature grounding, model use, simulation, validation, and knowledge reuse. This paper presents SCION (Scientific Collaborative Innovation with Agentic Organizational Nexus), an agentic scientific operating system that acts as an organizational nexus. Through a Science Agent serving as a Meta-Harness, SCION connects scientific tasks, tools, agents, artifacts, and memory, transforming research into an executable, auditable, and reusable operational process. At its core is the Research Execution Plan (REP), which compiles high-level scientific intent into staged objectives, dependencies, verification checkpoints, tool requirements, expected artifacts, and fallback conditions. SCION further integrates hierarchical multi-agent execution, profile-driven specialization, selective context construction, governed delegation, and layered epistemic memory to support long-horizon scientific work. We formulate discovery under SCION as Target-conditioned Inverse Search and extend it to hidden-target settings through batch active search under finite experimental budgets. Applications in materials analysis, molecule design, and protein or antibody screening, together with experiments on scientific reading, idea generation, molecule generation, and antibody screening, show that SCION outperforms existing autonomous research-agent baselines, especially in decomposition, verification, refinement, and memory reuse. Overall, SCION shifts AI from isolated tools toward a coordinated operational layer for traceable and reusable scientific innovation.

  • 30 authors
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Jul 6

The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search

AI is increasingly playing a pivotal role in transforming how scientific discoveries are made. We introduce The AI Scientist-v2, an end-to-end agentic system capable of producing the first entirely AI generated peer-review-accepted workshop paper. This system iteratively formulates scientific hypotheses, designs and executes experiments, analyzes and visualizes data, and autonomously authors scientific manuscripts. Compared to its predecessor (v1, Lu et al., 2024 arXiv:2408.06292), The AI Scientist-v2 eliminates the reliance on human-authored code templates, generalizes effectively across diverse machine learning domains, and leverages a novel progressive agentic tree-search methodology managed by a dedicated experiment manager agent. Additionally, we enhance the AI reviewer component by integrating a Vision-Language Model (VLM) feedback loop for iterative refinement of content and aesthetics of the figures. We evaluated The AI Scientist-v2 by submitting three fully autonomous manuscripts to a peer-reviewed ICLR workshop. Notably, one manuscript achieved high enough scores to exceed the average human acceptance threshold, marking the first instance of a fully AI-generated paper successfully navigating a peer review. This accomplishment highlights the growing capability of AI in conducting all aspects of scientific research. We anticipate that further advancements in autonomous scientific discovery technologies will profoundly impact human knowledge generation, enabling unprecedented scalability in research productivity and significantly accelerating scientific breakthroughs, greatly benefiting society at large. We have open-sourced the code at https://github.com/SakanaAI/AI-Scientist-v2 to foster the future development of this transformative technology. We also discuss the role of AI in science, including AI safety.

  • 8 authors
·
Apr 10, 2025 4

Towards Agentic Intelligence for Materials Science

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan, act, and learn across the full discovery loop. This survey advances a unique pipeline-centric view that spans from corpus curation and pretraining, through domain adaptation and instruction tuning, to goal-conditioned agents interfacing with simulation and experimental platforms. Unlike prior reviews, we treat the entire process as an end-to-end system to be optimized for tangible discovery outcomes rather than proxy benchmarks. This perspective allows us to trace how upstream design choices-such as data curation and training objectives-can be aligned with downstream experimental success through effective credit assignment. To bridge communities and establish a shared frame of reference, we first present an integrated lens that aligns terminology, evaluation, and workflow stages across AI and materials science. We then analyze the field through two focused lenses: From the AI perspective, the survey details LLM strengths in pattern recognition, predictive analytics, and natural language processing for literature mining, materials characterization, and property prediction; from the materials science perspective, it highlights applications in materials design, process optimization, and the acceleration of computational workflows via integration with external tools (e.g., DFT, robotic labs). Finally, we contrast passive, reactive approaches with agentic design, cataloging current contributions while motivating systems that pursue long-horizon goals with autonomy, memory, and tool use. This survey charts a practical roadmap towards autonomous, safety-aware LLM agents aimed at discovering novel and useful materials.

  • 21 authors
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Jan 29 2

Can LLMs Discover Scientific Laws in Real and Parallel Worlds?

Scientific equation discovery has long been central to scientific progress, proceeding through iterative cycles of hypothesis generation, observational testing, and refinement under scientific constraints. As LLM capabilities advance and their role in AI for Science expands, it remains an open problem whether they can genuinely discover scientific laws and how this ability should be evaluated. Existing evaluations, however, often either simplify discovery through synthetic settings or reuse published targets that may already be familiar to LLMs. We therefore introduce SCILAWS-BENCH, a benchmark for scientific law discovery built from published research and real scientific data. It comprises 118 problems drawn from 381 scientific papers, covering 291 candidate laws and roughly 8M real data points across six scientific disciplines. Each problem is instantiated in two complementary settings: (1) SCILAWS-REAL asks models to propose laws from fixed real observations and evaluates held-out predictive fit and scientific validity derived from the source literature, and (2) SCILAWS-PARALLEL asks models to actively query residual-calibrated worlds and recover synthesized hidden laws derived from published forms. This two-setting task design preserves each problem's scientific context while separately evaluating fixed-record law discovery and active recovery of a newly synthesized hidden law. We find that predictive fit can diverge from scientific validity, memorization shapes whether models reproduce or move beyond published formulas, and our best-of-N study reveals a selection bottleneck. Our work provides a paper-grounded benchmark and new empirical perspectives for evaluating AI for scientific discovery. Project page: https://yiyihum.github.io/SciLaws-Bench

  • 14 authors
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Aug 31

ProjectionBench: Evaluating Scientific Hypothesis Generation in LLMs Under Progressive Information Disclosure

Scientific discovery is an inherently creative and uncertain process, requiring reasoning beyond the recall of known knowledge. While many benchmarks have been proposed to evaluate large language model (LLM) performance on deep research tasks via multi-hop retrieval, their innovative reasoning abilities essential for true scientific discovery remain largely untested. We introduce a benchmark framework for evaluating model performance in scientific discovery and reasoning, building up from a raw problem to the classical null hypothesis test. In our framework, models initially receive only the topic and research question from a recent paper, with technical details progressively revealed. At each stage of information disclosure, the model is tasked with generating hypotheses that address the research question, which is compared with the conclusions from the original paper and evaluated via automated semantic similarity of constituent atomic claims. This progressive evaluation of semantic divergence from ground-truth conclusions enables assessment of a model's innovativeness (under minimal information) to grounded reasoning capabilities (under full experimental details), both critical for using LLMs for scientific discovery purposes. Our framework provides a foundation for systematically evaluating scientific reasoning and discovery capabilities in LLMs, crucial for advancing the development of next-generation AI scientist/co-scientist systems. Specifically, here we evaluate GPT-5, GPT-5.4, Gemini 2.5 pro, and Gemini 3.1 pro preview across 45 papers spanning bioactive materials, mechanical materials, and nanomaterials. We find that GPT-5.4 and Gemini 3.1 pro outperform their previous generation counterparts as expected, and GPT-5.4 in particular maintains 0.7 F1 score alignment with ground truth conclusions even under minimal context.

  • 3 authors
·
May 27

Autonomous Scientific Discovery via Iterative Meta-Reflection

Autonomous scientific discovery systems offer the potential to accelerate research by automating the process of hypothesis generation and validation. However, current systems operate within constrained search spaces or require predefined research questions, limiting their capacity for true open-ended inquiry. Furthermore, while they generate hypotheses iteratively, they largely lack the ability to explicitly synthesize their own accumulated findings to uncover complex, interconnected phenomena. We introduce DiscoPER, an autonomous large language model-powered framework that conducts open-ended research by dynamically generating and executing code to explore datasets without pre-specified research objectives. To ensure rigorous scientific validity, every proposed discovery must pass statistical testing. To overcome the limitations of isolated search, our framework introduces a second-order reasoning mechanism that periodically analyzes its own accumulated discoveries. By treating prior discoveries as empirical data, DiscoPER identifies structural patterns, confounds, and epistemic gaps, actively redirecting hypothesis exploration toward uncharted regions of the search space. The search space is further expanded by incorporating tool use, enabling the system to explore hypotheses beyond structured metadata by seamlessly processing and extracting useful information from multimodal sources like images. Evaluated on iNatDisco, a new multimodal ecological knowledge benchmark with pattern-level ground truth obtained from peer-reviewed literature, DiscoPER recovers 8 of 9 known patterns with a 72.7% hypothesis support rate, outperforming both classical causal discovery and LLM-guided baselines. Ablations show that DiscoPER scales with more data, and confirms the benefits of second-order meta-reflection.

  • 3 authors
·
Jun 30 2

FT-Dojo: Towards Autonomous LLM Fine-Tuning with Language Agents

Fine-tuning large language models for vertical domains remains a labor-intensive and expensive process, requiring domain experts to curate data, configure training, and iteratively diagnose model behavior. Despite growing interest in autonomous machine learning, no prior work has tackled end-to-end LLM fine-tuning with agents. Can LLM-based agents automate this complete process? We frame this as a substantially open problem: agents must navigate an open-ended search space spanning data curation from diverse data sources, processing with complex tools, building a training pipeline, and iteratively refining their approach based on evaluation outcomes in rapidly growing logs--an overall scenario far more intricate than existing benchmarks. To study this question, we introduce FT-Dojo, an interactive environment comprising 13 tasks across 5 domains. We further develop FT-Agent, an autonomous system that mirrors human experts by leveraging evaluation-driven feedback to iteratively diagnose failures and refine fine-tuning strategies. Experiments on FT-Dojo demonstrate that purpose-built fine-tuning agents significantly outperform general-purpose alternatives, with FT-Agent achieving the best performance on 10 out of 13 tasks across all five domains. Ablations show that the approach generalizes effectively to 3B models, with additional insights on data scaling trade-offs and backbone sensitivity. Case analyses reveal that agents can recover from failures through cumulative learning from historical experience, while also exposing fundamental limitations in causal reasoning--highlighting both the promise and current boundaries of autonomous LLM fine-tuning.

  • 7 authors
·
Mar 2

GLAM: Efficient Continual Learning at Scale via Grouped LoRA Adapter Merging

The ability to learn continuously over time remains a major challenge for modern machine learning systems, even in the era of Foundation Models. While the rich representations learned by large pre-trained models can partially mitigate catastrophic forgetting, they still struggle to adapt efficiently to evolving data distributions. A key challenge remains, how to continually add new knowledge to a large pretrained model in a way that is scalable and computationally efficient over long task sequences. In this work, we introduce GLAM, a simple and effective framework for class-incremental continual learning based on LoRA adapters merging. For each task, GLAM trains a lightweight low-rank adapter with an importance scalar, incurring minimal computational overhead. Adapters are then pruned, rescaled, and sequentially grouped to enable structured knowledge reuse and limit parameter growth. At inference, all groups are combined into a single module, ensuring constant computational cost regardless of the number of tasks. We evaluate GLAM on vision benchmarks with sequences of up to 50 tasks, significantly extending beyond standard protocols. GLAM achieves the highest accuracy across the evaluated benchmarks. Compared with the baseline attaining the highest average accuracy across benchmarks, it uses 16--19\% of the trainable parameters and reduces training time by approximately 63--74\%, demonstrating efficient and scalable continual learning. Our source code is publicly available at https://github.com/atlas-luiss/GLAM.

  • 6 authors
·
Aug 10

Knowledge-Centric Self-Improvement

Self-improving AI systems typically treat the agent as the object that improves, by optimizing prompts, workflows, harnesses, or even the agent's own code. This agent-centric view can make improvements expensive to maintain and difficult to transfer, because gains become tied to a particular agent design, task distribution, or adaptation run. We study a complementary paradigm: knowledge-centric self-improvement, in which agents remain generic and disposable while the persistent object is a curated knowledge base that agents can leverage for future tasks. We conduct controlled case studies to operationalize this idea via a simple protocol. Agents attempt one task, then contribute evidence-grounded insights to a shared knowledge base via task-level and cross-task forums, followed by knowledge distillation. Because self-improvement is contained in the knowledge rather than the agent, improvement can be more inspectable, transferable, and portable. Across abstract reasoning, coding, and terminal benchmarks, this protocol improves solve rates while reducing dollar cost relative to agent-centric baselines. The resulting distilled knowledge also transfers to held-out tasks and across LLM families, indicating that the improvement is not merely an LLM- or run-specific behavior. These results support a new view of self-improving agentic systems: progress can be driven primarily by the curated persistent knowledge. Code is available at https://github.com/recursive-knowledge/KSI.

  • 7 authors
·
Jul 20

Can Current Agents Close the Discovery-to-Application Gap? A Case Study in Minecraft

Discovering causal regularities and applying them to build functional systems--the discovery-to-application loop--is a hallmark of general intelligence, yet evaluating this capacity has been hindered by the vast complexity gap between scientific discovery and real-world engineering. We introduce SciCrafter, a Minecraft-based benchmark that operationalizes this loop through parameterized redstone circuit tasks. Agents must ignite lamps in specified patterns (e.g., simultaneously or in timed sequences); scaling target parameters substantially increases construction complexity and required knowledge, forcing genuine discovery rather than reliance on memorized solutions. Evaluating frontier models including GPT-5.2, Gemini-3-Pro, and Claude-Opus-4.5 under a general-purpose code agent scaffold, we find that all plateau at approximately 26% success rate. To diagnose these failures, we decompose the loop into four capacities--knowledge gap identification, experimental discovery, knowledge consolidation, and knowledge application--and design targeted interventions whose marginal contributions serve as proxies for corresponding gaps. Our analysis reveals that although the general knowledge application capability still remains as the biggest gap across all models, for frontier models the knowledge gap identification starts to become a major hurdle--indicating the bottleneck is shifting from solving problems right to raising the right problems for current AI. We release SciCrafter as a diagnostic probe for future research on AI systems that navigate the full discovery-to-application loop.

  • 12 authors
·
Apr 26